cANCA

cANCA, also referred to as cytoplasmic/classical antineutrophil cytoplasmic antibodies, demonstrate a diffusely granular staining pattern in indirect immunofluorescence assays (IFA).

The target antigen is most commonly proteinase 3 (PR3). cANCA are associated with Wegener’s granulomatosis.

Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s