Research Update: New Classification Criteria for Sjoegren’s Syndrome


Since the early 1960s almost a dozen different criteria for Sjögren’s syndrome (SS) have been published, both for classifying and for diagnosing that autoimmune disease. Recently, an international team of rheumatologists has published new classification criteria for Sjögren’s syndrome. In the April issue of the Arthritis Care & Research journal the authors propose clear and carefully worded guidelines.

Without question, these “new 2012 classification criteria for Sjögren’s syndrome” are urgently needed to better support etiologic and genetic research and therapeutic trials for Sjögren’s syndrome. Indeed, the new criteria are the first to be based solely on objective clinical tests!

Many other criterions have permitted various testing subjectivity to enable the classification of the disorder. In consequence, subjectivity has made standardisation of clinical trial inclusion something of a moving target, limiting comparability of research data across studies and impeding the needed robust clinical evaluation of possible new treatments. But criteria used for enrollment into clinical trials need to be clear, be easy to apply. And the new 2012 criteria agree to that demand. Continue reading

The 2010 ACR – EULAR Rheumatoid Arthritis Classification Criteria in brief


In the September issues of their journals Arthritis and Rheumatism and Annals of the Rheumatic Diseases the American College of Rheumatology (ACR) and the European League Against Rheumatism (EULAR) present a new set of criteria for the classification of rheumatoid arthritis (RA).

Why do wee need “new” criteria for the classification of RA?

The 1987 ACR criteria have been criticised for their lack of sensitivity, especially in early disease. They rather describe the symptoms of fully developed late-stage RA. During the past decade, RA treatment has undergone dramatic changes Continue reading